array-based dna methylation data infinium humanmethylation 450 beadchip (INFINIUM Inc)
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Array Based Dna Methylation Data Infinium Humanmethylation 450 Beadchip, supplied by INFINIUM Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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1) Product Images from "Mendelian inheritance of trimodal CpG methylation sites suggests distal cis-acting genetic effects"
Article Title: Mendelian inheritance of trimodal CpG methylation sites suggests distal cis-acting genetic effects
Journal: Clinical Epigenetics
doi: 10.1186/s13148-016-0295-1
Figure Legend Snippet: Potential processes leading to a genetically driven methylation site. Three potential processes can lead to an association of a genetic variant and a trimodal distribution of CpG methylation: (1) “Spillover from a neighboring CpG site” that is deleted by a SNP by processes of local methylation maintenance, (2) SNP-induced changes in gene expression activity may have a feedback effect on DNA methylation due to differences in the translation machinery that leaves methylation marks on the DNA, and (3) SNP-induced changes in gene function may induce different levels of gene expression that are implemented by changes in promoter gene methylation
Techniques Used: Methylation, Variant Assay, CpG Methylation Assay, Expressing, Activity Assay, DNA Methylation Assay